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80Yr male with altered sensorium

 This is an online Blog book to discuss our patients deidentified health data shared after taking his/ her guardians to sign an informed consent


Here we discuss our patient problems through a series of inputs from the available Global online community of experts with n aim to solve those patient clinical problems with the current best evidence-based input
This Blog also reflects my patient-centred online learning portfolio.
Your valuable input on the comment box is welcome
 I have been given this case to solve in an attempt to understand the topic of " Patient clinical data analysis" to develop my competence in reading and comprehending clinical data including history, clinical findings, investigations and come up with a diagnosis and treatment plan


CHEIF COMPLAINTS:

Fever since 10 days 

Burning micturition since 1 day

Left loin pain since 1 day 

Decreased urine output since 1day

Blood in urine since 3 hrs


HISTORY OF PRESENTING ILLNESS

A 80Yr male, agriculture by occupation,clinically presented to casualty with complaints of high grade fever since 10 days (25th sep - 5th oct) , not associated with cold / cough/abdominal pain.which was releived on taking antipyretics and oral antibiotics . Afterday10 of illness his fever subsided . After 3 days i.e he had symptoms of burning micturition, abdominal distention and left loin pain , non radiating, dragging type and decreased urine output having dark yellowish coloured urine since 1 day. 




PAST ILLNESS:

K/c/o : Hypertension since 1yr and taking medications irregularly 

Right lower end of tibial fracture 1 yr ago 

Not a K/c/o TB/asthma/CAD/CVD/epilepsy/ thyroid disorders


PERSONAL HISTORY:

80Yr male, married , agriculture by occupation, has normal appetite, mixed diet , regular bowels( not passed stools today), decreased urine output,no allergies, occasionally drinks ( once in a week) I.e (3.6 units of alcohol/week)

Smokes 10beedi/day (30 pack years)


No significant Family history


ON GENERAL PHYSICAL EXAMINATION 

Patient was drowsy , incoherent

GCS - E2( eye opening to pain)

            V2( verbal response- volcalises i.e                         makes sounds but no word)

             M3( motor response I.e abnormal flex     

ion to pain)

pallor present 

No icterus , cyanosis , clubbing, lymphadenopathy,edema


VITALS:  

On presentation 

Temp.-99.7

Bp- 120/90mmhg

PR-98bpm

RR-18cpm

Grbs-116mg/dl


  












SYSTEMIC EXAMINATIONS 

CVS: S1s2 heard

R/S : BAE+ , 

right infraxillary area crepts +

decreased breath sounds, 

P/A :scaphoid ,soft ,tenderness at umbilicus ,bowel sounds heard, stools passed yesterday 








COURSE IN HOSPITAL 

A 80Yr male came to casualty with above mentioned complaints. Upon arrival initial assessment was done. He was started on intravenous fluid therapy. Urine analysis and culture and sensitivity were sent . Urine analysis showed 10-1


febrile to touch 

GCS : E4V5M6

PR:142bpm

Bp:110/70mmhg

RR:18cpm

Pleural tap was done on 15/10/22


X-ray after pleural tap








TREATMENT:

1.IVF 3% NS @ 75ml/hr

2.INJ.MEROPENEM 500mg /IV /Bd for7 days

3. INJ.PAN40mg /iv/bd

4.inj. Tramadol 1Amp in 100ml Ns/iv/od

5.inj. NEOMOL 1gm 

6. Tab.dolo 650 mg/po/TID

7. Ryles  tube insertion 

8. Tab.  Azithromycin 500mg /po/od for 6 days

9. Inj. Vancomycin 1gm /iv/bd for 4 days

1st,3rd

2nd,4th 

X-ray on 16/10/22


Chest X-ray PA VIEW SUPINE POSITION TAKEN ON 17/10/22




Pleural fluid(EXUDATE)




Pleural fluid analysis- EXUDATE




Day 8
2nd time Pleural tap was done on 18/10/22



X-ray after pleural tap(2nd)

   
Patient developed pneumothorax 
Then after taking consent an ICD is placed in 5th ICS in mid axillary line



Fluid collected through ICD

( transudate)







Pleural fluid analysis:

Transudate






USG abdomen was done on 18/10/22




Ascitic Tap (diagnostic)was done on18/10/22
And sent for cytology, culture sensitivity, cell count





Day :9


S :  PAIN at site of ICD insertion, fever spike -yesterday 8pm 


O:

Pt c/c/c 

Bp - 110/70mmhg

PR - 110bpm

RR- 22cpm

Temp-98F

Spo2 - 92 at room air

CVS: S1S2+ loud s1@ aortic  and pulmonary area

apex beat at left 5th intercoastal space extended lateral to MCL

RS: BAE+

Inspection: Respiratory movements slightly more on right compared to left chest 

Crowding of ribs present

ICD- @ 5th Intercostal space @ mid axillary  line

 CREPTS AT 

LEFT INFRAAXILLARY AREA, IMA,ISA

RIGHT ISA,IMA


P/A: SOFT,BS+,Tenderness on palpation around umbilicus , stools not passed-D1

CNS: HMF INTACT 

          NO FND 

Input : 2300ml

Output: 1200ml








DIAGNOSIS:


ALTERED SENSORIUM SECONDARY TO ?HYPONATREMIA (resolved)- 

WITH CAP (RIGHT UL ANT LEFT LUNG)

? SEPTIC ENCEPHALOPATHY -LEFT PYELONEPHRITIS ( resolving)

WITH PRE RENAL AKI

with MICROCYTIC HYPOCROMIC ANEMIA SECONDARY TO  ?IRON DEFICIENCY 

? ANEMIA OF CHRONIC DISEASE 

WITH LEFT EMPYEMA 

WITH PNEUMOTHORAX WITH ICD DAY1

with k/c/o COPD and HTN 


 Treatment 


1)ALLOW ORAL FEEDS

2)IVF -NS/RL  @50ml/hr 

3) TAB. MIRTRAZAPINE 7.5mg/PO/HS

4)INJ. MEROPENEM 500 MG IV/BD (D10)

5) INJ. PAN 40MG IV/OD

6) INJ. TRAMADOL 1 AMP IN 100ML NS/IV/OD

7) INJ. VANCOMYCIN 1Gm/IV/BD(D7)

8) TAB. DOLO 650MG PO/ TID If temp.> 100F

9) NEB WITH DUOLIN 6th HOURLY and BUDECORT 8tH HOURLY 

10)VITAL + I/O CHARTING HOURLY 

11)ICD care 

bag always below waist 

Cap always open 

Check air coloum movement 

Maintain under water seal 

12)O2 inhalation with 2-4 lit

  1. Syp . POTCLOR 10ml in glass of water.

20/10/22 
ICU BED NO.6!
Day :11

S :  abdominal pain

O:
Pt c/c/c 
Bp - 120/70mmhg
PR - 112bpm
RR- 23cpm
Temp-100F
Spo2 - 90at room air ; 97% with 2lit O2
CVS: S1S2+ loud s1@ aortic  and pulmonary area
apex beat at left 5th intercoastal space extended lateral to MCL
RS: BAE+
Inspection: Respiratory movements slightly more on right compared to left chest 
 Auscultation:CREPTS AT 
LEFT INFRAAXILLARY AREA, IMA,ISA
RIGHT ISA,IAA

P/A: scaphoid , SOFT,BS+,Tenderness ++ diffuse 
CNS: HMF INTACT 
          NO FND 
Input : 1175ml 
Output: 990ml


A
ALTERED SENSORIUM SECONDARY TO ?HYPONATREMIA (resolved)- 
WITH CAP (RIGHT UL ANT LEFT LUNG) SECONDARY TO KLEBSIELLA PNEUMONIA
SPONTANEOUS BACTERIAL PERITONITIS -LEFT PYELONEPHRITIS WITH PRE RENAL AKI ( resolving)
WITH RIGHT HEART FAILURE SECONDARY TO CORPULMONALE
with MICROCYTIC HYPOCROMIC ANEMIA SECONDARY TO  ?IRON DEFICIENCY 
? ANEMIA OF CHRONIC DISEASE 
WITH LEFT EMPYEMA 
WITH PNEUMOTHORAX WITH ICD DAY3
with k/c/o COPD and HTN 

 


P
*
INJ. COLISTNMETHATE SODIUM 4.5 MIU./.      Iv/OD/OVER 30MIN in100ML NS (DAY3)

Ambulization , wheel chair mobilization


21/10/22

21/10/22 
AMC BED NO. I
Day :12

S :  Diffuse abdominal pain

O:
Pt c/c/c 
Bp - 110/70mmhg
PR - 21bpm
RR- 21cpm
Temp-98.7F
Spo2 - 97at room air 
CVS: S1S2+ loud s1@ aortic  and pulmonary area
apex beat at left 5th intercoastal space extended lateral to MCL
RS: BAE+
Inspection: Respiratory movements slightly more on right compared to left chest 
On percussion: left4th,5th ICS - dull
 Auscultation:decreased breath sounds at IMA,ISA
CREPTS AT 
LEFT INFRAAXILLARY AREA, IMA,ISA
RIGHT IAA

P/A: scaphoid , SOFT,BS+,Tenderness + bowel sounds sluggish 
CNS: HMF INTACT 
          NO FND 
Input : 975ml
Output: 1200ml


A
ALTERED SENSORIUM SECONDARY TO ?HYPONATREMIA (resolved)- 
WITH CAP (RIGHT UL ANT LEFT LUNG) SECONDARY TO KLEBSIELLA PNEUMONIA
SPONTANEOUS BACTERIAL PERITONITIS  -LEFT HYDROURETERO NEHROSIS
 WITH PRE RENAL AKI ( resolving)
WITH RIGHT HEART FAILURE SECONDARY TO CORPULMONALE
with MICROCYTIC HYPOCROMIC ANEMIA SECONDARY TO  ?IRON DEFICIENCY 
? ANEMIA OF CHRONIC DISEASE 
WITH LEFT EMPYEMA 
WITH PNEUMOTHORAX WITH ICD DAY4
WITH GRADE I BED SORE
with k/c/o COPD and HTN 

 


P
1. NBM TILL FURTHER ORDERS (I/v/o diffuse abdominal pain, bowel wall edema)
2)IVF -NS/RL  @50ml/hr 
3) PROTIEN X- powder 2 scoops + 100ml milk
4) BUSCOPAN 20MG/IM/SOS
5) INJ. PAN 40MG IV/OD
6) TAB. MITRAZAPINE 7.5Mg po/Hs
8) TAB. DOLO 650MG PO/ TID If temp.> 100F
9) NEB WITH DUOLIN 6th HOURLY and BUDECORT 8tH HOURLY 
10)VITAL + I/O CHARTING HOURLY 
11)ICD care 
bag always below waist 
Cap always open 
Check air coloum movement 
Maintain under water seal 
12)O2 inhalation with 2-4 lit
13. Ambulation, wheel chair mobilization

* . COLISTNMETHATE SODIUM 
CBNAAT showed Tuberculosis positive, sensitive to  rifampicin 




22/10/22 
AMC BED NO. 1 
Day :13
80/Male
S :  Decrease appetite 
       loose stools since Yesterday (5episodes)
O:
Pt c/c/c 
Bp - 110/70mmhg
PR - 124bpm
RR- 19cpm
Temp-101F
Spo2 - 96at room air 
CVS: S1S2+ loud s1@ aortic  and pulmonary area
apex beat at left 5th intercoastal space extended lateral to MCL
RS: BAE+
Inspection: Respiratory movements slightly more on right compared to left chest 
On percussion: left4th,5th ,6th ICS - dull
 Auscultation:decreased breath sounds at IMA,ISA
CREPTS AT 
LEFT INFRAAXILLARY AREA, IMA,ISA
RIGHT IAA CREPTS
P/A: scaphoid , SOFT,BS+,Tenderness + ,bowel sounds+
CNS: HMF INTACT 
          NO FND 
Input : 975ml
Output: 1200ml
A
ALTERED SENSORIUM SECONDARY TO ?HYPONATREMIA (resolved)- 
WITH CAP (RIGHT UL ANT LEFT LUNG) SECONDARY TO KLEBSIELLA PNEUMONIA
SPONTANEOUS BACTERIAL PERITONITIS  -LEFT HYDROURETERO NEHROSIS
 WITH NON OLIGURIC AKI
WITH RIGHT HEART FAILURE SECONDARY TO CORPULMONALE
with MICROCYTIC HYPOCROMIC ANEMIA SECONDARY TO  ?IRON DEFICIENCY 
? ANEMIA OF CHRONIC DISEASE 
WITH LEFT EMPYEMA 
WITH GRADE I BED SORE
PULMONARY TUBERCULOSIS 
with k/c/o COPD and HTN 



P
1. Allow oral fluids 2lit/day
2)IVF -NS/RL with optineuron  @50ml/hr 
3) Tab. SPOROLAC po/sos
4) BUSCOPAN 20MG/IM/SOS
5) INJ. PAN 40MG IV/OD
6) TAB. MITRAZAPINE 7.5Mg po/Hs
8) TAB. DOLO 650MG PO/ TID If temp.> 100F
9) NEB WITH DUOLIN 6th HOURLY and BUDECORT 8tH HOURLY 
10)VITAL + I/O CHARTING HOURLY 
12)O2 inhalation with 2-4 lit
13. Ambularono , wheel chair mobilization 
14. PROTIEN X- powder 2 scoops + 100ml milk 
15. ATT.—TAB. Isoniazide 215mg/po/od , 
16. Tab. RIFAMPICIN 430mg/po/od
17. Tab.pyrizinamide 1125mg/po/od
18. Tab.Ethambutol 540mg/po/od

25/10/22
Day :16
S : pruritis, no fever spike , Right hypochondriac pain
O:
Pt c/c/c 
Bp - 110/80mmhg
PR - 120pm
RR-24cpm
Spo2 - 96%at room air 
CVS: S1S2+ loud s1@ aortic  and pulmonary area
apex beat at left 5th intercoastal space extended lateral to MCL
Parasternal heave +
RS: BAE+
On percussion: less  resonant on left side
 Auscultation: BAE+ no abnormal sounds heard
P/A: scaphoid , SOFT,BS+,Tender right hypocondrium ,4episodes of stools
CNS: HMF INTACT 
          NO FND 
Input : 2900ml
Output: 2050ml
A
PULMONARY TUBERCULOSIS on ATT( Started on 22/10/22)
Left CAP secondary to klebsiella pneumonia with left pneumothorax (resolved)
With left hydrouretronephrosis
With non oliguric AKI
With culture negative neutrocytic ascitis 
With right heart failure secondary to 
Cor-Pulmonale
With COPD with Hyponatremia (resolved)
With k/c/o HTN with grade 1 bed sore

P
1. Allow oral fluids 2lit/day
2.IVF -NS/RL  @50ml/hr 
3.BUSCOPAN 20MG/IM/SOS
4.INJ. PAN 40MG IV/OD
5.TAB. MITRAZAPINE 7.5Mg po/Hs
6.TAB. DOLO 650MG PO/ TID If temp.> 100F
7.NEB WITH DUOLIN 6th HOURLY and BUDECORT 8tH HOURLY 
8.VITAL + I/O CHARTING HOURLY 
9.cap. Kedotil 100mg/po/sos(if loose stools+)
10. Ambulation,wheel chair mobilization 
11.PROTIEN X- powder 2 scoops + 100ml milk 12.ATT.(day4)
TAB. Isoniazide 300mg/po/od , 
Tab. RIFAMPICIN 450mg /po/od
13.Tab. Benadone 40mg/po/od
14.Inj.Zofer 4mg /iv/sos


25/10/22 
Day :16
S : pruritis, no fever spike , Right hypochondriac pain
O:
Pt c/c/c 
Bp - 110/80mmhg
PR - 120pm
RR-24cpm
Spo2 - 96%at room air 
CVS: S1S2+ loud s1@ aortic  and pulmonary area
apex beat at left 5th intercoastal space extended lateral to MCL
Parasternal heave +
RS: BAE+
On percussion: less  resonant on left side
 Auscultation: BAE+ no abnormal sounds heard
P/A: scaphoid , SOFT,BS+,Tender right hypocondrium ,4episodes of stools
CNS: HMF INTACT 
          NO FND 
Input : 2900ml
Output: 2050ml
A
PULMONARY TUBERCULOSIS on ATT( Started on 22/10/22)
Left CAP secondary to klebsiella pneumonia with left pneumothorax (resolved)
With left hydrouretronephrosis
With non oliguric AKI
With culture negative neutrocytic ascitis 
With right heart failure secondary to 
Cor-Pulmonale
With COPD with Hyponatremia (resolved)
With k/c/o HTN with grade 1 bed sore

P
1. Allow oral fluids 2lit/day
2.IVF -NS/RL  @50ml/hr 
3.BUSCOPAN 20MG/IM/SOS
4.INJ. PAN 40MG IV/OD
5.TAB. MITRAZAPINE 7.5Mg po/Hs
6.TAB. DOLO 650MG PO/ TID If temp.> 100F
7.NEB WITH DUOLIN 6th HOURLY and BUDECORT 8tH HOURLY 
8.VITAL + I/O CHARTING HOURLY 
9.cap. Kedotil 100mg/po/sos(if loose stools+)
10. Ambulation,wheel chair mobilization 
11.PROTIEN X- powder 2 scoops + 100ml milk 12.ATT.(day4)
TAB. Isoniazide 300mg/po/od , 
Tab. RIFAMPICIN 450mg /po/od
13.Tab. Benadone 40mg/po/od
14.Inj.Zofer 4mg /iv/sos

https://nehareddygaddam.blogspot.com/2022/10/80yr-male-with-altered-sensorium.html




26/10/22 

Day :17

S : pruritis, no fever spike , Right hypochondriac pain, loose stools(?antibiotic induced?)

O:

Pt c/c/c 

Bp - 110/60mmhg

PR - 136pm

RR-26cpm

Spo2 - 97%at room air 

CVS: S1S2+ loud s1@ aortic  and pulmonary area

apex beat at left 5th intercoastal space extended lateral to MCL

Parasternal heave +

RS: BAE+




On percussion: less  resonant on left side

 Auscultation: BAE+ no abnormal sounds heard,decreased breath sounds in IAA,IMA

P/A: scaphoid , SOFT,BS+,Tender right hypocondrium ,episodes of loose stools

CNS: HMF INTACT 

          NO FND 

Input : 2500ml

Output: 2000ml

A

PULMONARY TUBERCULOSIS on ATT( Started on 22/10/22)

Left CAP secondary to 

klebsiella pneumonia superinfection 

with left pneumothorax (resolved)

With left hydrouretronephrosis

With non oliguric AKI

With culture negative neutrocytic ascitis 

With right heart failure secondary to 

Cor-Pulmonale

With COPD with Hyponatremia (resolved)

With k/c/o HTN with grade 1 bed sore


P

  1. Allow oral fluids 2lit/day

3.BUSCOPAN 20MG/IM/SOS

4.INJ. PAN 40MG IV/OD

5.TAB. MITRAZAPINE 7.5Mg po/Hs

6.TAB. DOLO 650MG PO/ TID If temp.> 100F

7.NEB WITH DUOLIN 6th HOURLY and BUDECORT 8tH HOURLY 

8.VITAL + I/O CHARTING HOURLY 

9.cap. Kedotil 100mg/po/sos(if loose stools+)

  1. Ambulation,wheel chair mobilization 

11.PROTIEN X- powder 2 scoops + 100ml milk 12.ATT.(day5)

TAB. Isoniazide 300mg/po/od , 

Tab. RIFAMPICIN 450mg /po/od

TAB.Pyrazinamide 1500mg/po/od

TAB. Ethambutol 400mg /po/od

13.Tab. Benadone 40mg/po/od

14.Inj.Zofer 4mg /iv/sos



80 year male clinically presented with above mentioned complaints. Upon admission chest x ray was done which showed pneumothorax, for which pulmonology refferal was taken for emergency needle decompression and tube thoroacostomy. Under asceptic conditions ICD tube was placed at left 5th ICS at mid axillary line, and ICD tube was connected to underwater seal. USG Abdomen showed Ascites with septae and ascitic tap was done and sent for culture  Pleural fluid was sent for CBNAAT and pleural analysis.
pleural fluid culture and sensitivity showed growth of Klebsiella pneumonia which was resistent to Meropenem, so patient was started on Colistin for 3 days.Pleural fluid analysis for CBNAAT showed Positive for Mycobacterium tuberculosis and sensitive to Rifampacin. His serum creatinine was 2.5 mg/dl and was started on ATT at renal modified doses from 22/10/2022. 
2d echo was done on 19/10/2022 which showed e/o 
No RWMA; Mild LVH; Mild to Moderate TR with PAH; Sclerotic AV; EF 58%; Diastolic dysfunction.
During hospital stay patient was treated with antitubercular drug, Intravenous antibiotics and other supportive medications. Their is clinical improvement of the patient.
On serial chest x ray their is improvement in the left lung consolidation. His Sr.creatinine was in increasing trend, so pulmonology cross consultation was taken, the pulmonologist was advised to stop pyrazinamide and Ethambutol. The patient condition has been improved, so being discharged in a hemodynamically stable condition.


Psychiatry cross consultation was taken in view of tobacco craving and advise followed

Review in Pulmonology OPD after 3 days .

EXTRAPULMONARY TUBERCULOSIS;
LEFT CAP SECONDARY TO KLEBSIELLA PNEUMONIA ( SUPERINFECTION);
LEFT PNEUMOTHORAX ( RESOLVED);
CULTURE NEGATIVE NEUTROCYTIC ASCITES; 
DRUG INDUCED NON OLIGURIC AKI;
HEART FAILURE SECONDARY TO CORPULMONALE WITH COPD;
 HYPONATREMIA (RESOLVED); K/C/O HTN.



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